Sustained HSP25 Expression Induces Clasmatodendrosis via ER Stress in the Rat Hippocampus

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Sustained HSP25 Expression Induces Clasmatodendrosis via ER Stress in the Rat Hippocampus

Heat shock protein (HSP) 25 (murine/rodent 25 kDa, human 27 kDa) is one of the major astroglial HSP families, which has a potent anti-apoptotic factor contributing to a higher resistance of astrocytes to the stressful condition. However, impaired removals of HSP25 decrease astroglial viability. In the present study, we investigated whether HSP25 is involved in astroglial apoptosis or clasmatode...

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ژورنال

عنوان ژورنال: Frontiers in Cellular Neuroscience

سال: 2017

ISSN: 1662-5102

DOI: 10.3389/fncel.2017.00047